فایل ورد (word) مقاله Clinical Significance of Axin and ?-catenin Protein Expression in Primary Hepatocellular Carcinomas دارای 8 صفحه می باشد و دارای تنظیمات در microsoft word می باشد و آماده پرینت یا چاپ است
فایل ورد فایل ورد (word) مقاله Clinical Significance of Axin and ?-catenin Protein Expression in Primary Hepatocellular Carcinomas کاملا فرمت بندی و تنظیم شده در استاندارد دانشگاه و مراکز دولتی می باشد.
توجه : در صورت مشاهده بهم ريختگي احتمالي در متون زير ،دليل ان کپي کردن اين مطالب از داخل فایل ورد مي باشد و در فايل اصلي فایل ورد (word) مقاله Clinical Significance of Axin and ?-catenin Protein Expression in Primary Hepatocellular Carcinomas،به هيچ وجه بهم ريختگي وجود ندارد
بخشی از متن فایل ورد (word) مقاله Clinical Significance of Axin and ?-catenin Protein Expression in Primary Hepatocellular Carcinomas :
سال انتشار : 2012
تعداد صفحات :8
The aim of the present research was to investigate clinicopathologic correlations of immunohistochemically-demonstrated axin (axis inhibition) and -catenin expression in primary hepatocellular carcinomas (HCCs), in comparison with paraneoplastic, cirrhotic and normal liver tissues. Variation in Axin expression across groups were significant (P < 0.01), correlating with alpha fetoprotein (AFP), HBsAg, cancer plugs in the portal vein, and clinical stage of HCCs(P < 0.05); however, there were no links with sex, age, and tumour size (P > 0.05). Differences in cell membrane -catenin expression were also statistically significant (P < 0.01), again correlated with AFP, HBsAg, cancer plugs in the portal vein, and clinical stage in HCCs (P < 0.05) but not with sex, age, and tumour size (P > 0.05). Axin expression levels in tissues with reduced membrane -catenin were low (P < 0.05), also being low with nuclear -catenin expression (P < 0.05). Axin and -catenin may play an important role in the genesis and progression of HCC via the Wnt signal transmission pathway. Simultaneous determination of axin, -catenin, AFP, and HBsAg may be useful for early diagnosis, and metastatic and clinical staging of HCCs.