فایل ورد (word) مقاله Predictive Role of Tumor Size in Breast Cancer with AxillaryLymph Node Involvement - Can Size of Primary Tumor beused to Omit an Unnecessary Axillary Lymph Node Dissection? دارای 10 صفحه می باشد و دارای تنظیمات در microsoft word می باشد و آماده پرینت یا چاپ است
فایل ورد فایل ورد (word) مقاله Predictive Role of Tumor Size in Breast Cancer with AxillaryLymph Node Involvement - Can Size of Primary Tumor beused to Omit an Unnecessary Axillary Lymph Node Dissection? کاملا فرمت بندی و تنظیم شده در استاندارد دانشگاه و مراکز دولتی می باشد.
توجه : در صورت مشاهده بهم ريختگي احتمالي در متون زير ،دليل ان کپي کردن اين مطالب از داخل فایل ورد مي باشد و در فايل اصلي فایل ورد (word) مقاله Predictive Role of Tumor Size in Breast Cancer with AxillaryLymph Node Involvement - Can Size of Primary Tumor beused to Omit an Unnecessary Axillary Lymph Node Dissection?،به هيچ وجه بهم ريختگي وجود ندارد
بخشی از متن فایل ورد (word) مقاله Predictive Role of Tumor Size in Breast Cancer with AxillaryLymph Node Involvement - Can Size of Primary Tumor beused to Omit an Unnecessary Axillary Lymph Node Dissection? :
سال انتشار : 2013
تعداد صفحات :10
Background: Breast cancer is the most common cancer among women worldwide. The aim of this study wasto investigate the relationship between tumor size and axillary lymph node involvement (ALNI) in patients withinvasive lesions, to find the best candidates for a full axillary dissection. Additionally, we evaluated the associationbetween tumor size and invasive behavior. The study was based on data from 789 patients with histopathologicallyproven invasive breast cancer diagnosed in Shohada University hospital in Tehran, Iran (1993-2009). Cinicaland histopathological characteristics of tumors were collected. Patients were divided into 6 groups accordingto primary tumor size: group I (0.1-1cm), II (1.1-2cm), III (2.1-3cm), IV (3.1-4cm), V (4.1-5cm) andVI (>5cm). The mean(±SD) size of primary tumor at the time of diagnosis was 3.59±2.69 cm that graduallydeclined during the course of study. There was a significant correlation between tumor size and ALNI (p<0.001).A significant positive correlation between primary tumor size and involvement of surrounding tissue was alsofound (p<0.001). The mean number of LNI in group VI was significantly higher than other groups (p<0.05).Weobserved more involvement of lymph nodes, blood vessels, skin and areola-nipple tissue with increase in tumorsize.We found 15.3% overall incidence of ALNI in tumors 2 cm, indicating the need for more investigation toomit full axillary lymph node dissection with an acceptable risk for tumors below this diameter. While in patientswith tumors 2 cm, 84.3% of them had nodal metastases, so the best management for this group would be a fullALND. Tumor size is a significant predictor of ALNM and involvement of surrounding tissue, so that an exactestimation of the size of primary tumor is necessary prior to surgery to make the best decision for managementof patients with invasive breast cancer.